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Farmer with tablet and tractor spraying field
Farmer with tablet and tractor spraying field

If you could do something twice as fast in your fields as you normally do, with the same results, you would do it, right? What about three times faster?

What if, by doing something more efficiently, you could also improve the overall results? Well, believe it or not, it’s possible.

Tank mixing agricultural inputs, including biologicals, can save time and be economical. You can spray your fields more efficiently and potentially improve product efficacy by tank-mixing agricultural products.

Don’t run to your sprayer just yet! If done wrong, the results can range from disappointing to disastrous. Whether an incompatible mix clogs your machinery or causes crop injury due to chemical incompatibility, tank-mixing with products new to your operation requires correct handling and attention to mixing instructions. Attention to detail is crucial to reaping the benefits that can positively or negatively impact yield.

Here are the basic principles of tank-mixing every grower should know to ensure a successful tank mix and application. 

What is tank-mixing?

Tank-mixing is when a grower mixes multiple agricultural inputs into a single tank to make a single spray application for his/her fields. This allows the grower to treat various stressors, manage fertility, or enhance the efficacy of other products in a single pass.

Mixing multiple products together in one tank could include a combination of products like pesticides, fertilizers, macro-micronutrients, soil microbial foods, biostimulants, plant growth regulators, and adjuvants.

Helpful Terms for Tank-Mixing

Suspension: a mixture of fluid and solid particles

Carrier: primary material, such as water or fertilizer, used to allow pesticides, herbicides, fungicides, etc., to be dispersed effectively

Adjuvant: a performance-enhancing substance added to the crop input spray mix

Agitate: stirring or shaking the tank

What can go in a tank mix?

Agricultural products commonly found in a tank mix include:

  • Fertilizers
  • Herbicides
  • Pesticides
  • Fungicides
  • Adjuvants
  • Surfactants
  • Plant growth regulators
  • Soil microbial foods
  • Spray dyes
  • Micronutrients
  • Macronutrients
  • Biostimulants
  • Biologicals
  • Enzymes
  • Inoculants
  • Seaweeds
  • Kelps
  • Humic Acids
  • Fulvic Acids
  • Other crop input solutions

Growers normally use water or fertilizer as the main carrier of the tank mix to combine solutions together.

It’s important to know the water and other value-added products’ pH level, mineral content, and temperature to avoid creating a compatibility issue. A proper pH level and temperature are needed for the products to mix and dissolve efficiently. When mixing with living biologicals, pH can impact when these products become active and release their active ingredient, and pH can have an impact on the viability of these organisms. For best practice, follow manufacturing instructions to know what pH is needed when adding living biologicals.

The mineral levels can compromise applications by mineral bonding. High levels of calcium, aluminum, iron, magnesium, chlorine, and sodium in hard water can have a negative impact on herbicide, pesticide, and biological performance or inhibit the compatibility of the products.

When mixing any products with fertilizer as the carrier – rather than water – keep an eye on pH levels due to these products having very high or low pH levels. Many products, like biologicals, require pH stabilization before mixing with other agricultural inputs.

Different Formulation Types

The type of formulation, e.g., powder, liquid, etc., of each product determines the mixing order of each product into the carrier. Here are some of the most common formulation types.





Dry Flowables

Clumps are more easily broken up and recovered than WP


Emulsified Concentration

Phytotoxicity risk


Emulsion in Water


Flowable Liquid




Oil Dispersion




Suspended Concentrates

Easiest to apply                      Lowest callenge risk


Soluble Granule


Soluble Liquids

Easiest to apply                      Lowest callenge risk


Soluble Powder


Water Dispersible Granule


Water Soluble Packet


Wettable Powder

Creates the greatest challenge due to clumping

To know which products to apply first, refer to the W.A.L.E.S. acronym described later in this blog post.

Benefits of Tank-mixing Agricultural Products

When it comes to tank-mixing, the wide range of benefits far outweighs the risks, especially since risks can be avoided. From cost-savings to improved efficacy, tank-mixing benefits both growers and crop performance.

Attack Target Threats to Your Crops

From pesticides to fungicides, tank-mixing can support your crops by targeting pests lurking in your fields. A grower can use a complex tank mix to target multiple biotic and abiotic stressors in one treatment, rather than relying on multiple treatments and field passes – improving overall crop performance and implementing more sustainable agricultural practices. It’s also an easy way to improve your resistance management from different angles and take out hard-to-kill pests.

Increase Cost Savings

Tank-mixing agricultural inputs gives a grower labor and fuel cost savings. It decreases the cost of application by reducing total passes in a growing season. By driving heavy machinery in your field less frequently, you are able to minimize crop damage and reduce soil compaction.  Efficiency saves growers money and adds to the bottom line!

Improve Efficacy

When mixed, some agricultural products create synergy. This means the inputs provide better results when applied together rather than alone. Spray adjuvants, for example, can enhance the efficacy of active ingredients.

Protect Your Soil

Heavy machinery passes contribute to soil compaction, which damages your soil’s microbiome – an ecosystem that supports crops when activated. Tank-mixing helps growers reduce the number of passes in a field by applying a more diversified treatment with a single pass, mitigating compaction damage.

Protect Growers

Mixing agricultural products is good for growers because each grower can apply a timely application based on weather conditions, crop stage, or pest life cycle.

Common Agricultural Input and Tank-Mixing Mistakes to Avoid

Tank-mixing mistakes can result in compatibility issues that impact how a product is dispersed, mixed, and delivered, which may negatively impact the product’s overall performance in the field. Each product has a set of complex chemical structures. When new agricultural products are added to your tank, the likelihood of a compatibility issue arising increases.

These mistakes can occur when combining inputs or by not taking the proper steps when evaluating new tank-mix partners.

An input mistake could look like:

  • Ignoring the label and creating increased phytotoxicity
  • Creating an antagonistic effect, i.e., products working against each other, which reduces efficacy
  • Creating a physical reaction resulting in an un-sprayable sludge
  • Killing off beneficial microbes by combining an antimicrobial with a biological

Most of these problems can be avoided by reading the label and adhering to restrictions or best practices when mixing multiple products. Always examine a label closely to avoid damaging your crops or machinery.

A mixing mistake could look like:

  • Neglecting to rinse and clean out the spray tank before use
  • Using a poor-quality water source for the carrier
  • Improperly agitating product
  • Mixing products in low temperatures

There are two kinds of incompatibilities that can result from input or mixing mistakes: physical incompatibilities and chemical incompatibilities.

Physical and Chemical Incompatibilities

Physical incompatibilities occur when products or ingredients do not mix properly, which can block the spray systems and disrupt application. Signs you may have a physical incompatibility include:

  • Products will not suspend
  • Products clump together
  • Products will not completely dissolve
  • Oil residue appears in the tank
  • Products separate into layers
  • Solution foams excessively

Chemical incompatibilities occur when the spray mixes and looks fine in the tank or jar test, but the mixed products are chemically incompatible. Just because a mix looks fine doesn’t mean it is.

Sometimes, a chemical incompatibility reduces biological activity or efficacy. Other times, a chemical incompatibility can injure or kill crops. It can take hours or even days to notice if a chemical incompatibility has taken place after an application.

If you discover there is a physical or chemical incompatibility in your mixture, all gels and solids must be flushed from tanks, filters, screens, and nozzles. Consult with a chemical company representative or agronomist before dumping an incompatible mix.

The time lost, and cleanup can be expensive, and the materials can be difficult to dispose of. Work with a professional to ensure it’s done right. Otherwise, you could make a bad situation worse.

20 Ways to Avoid Tank-Mixing Incompatibilities

  1. Follow the labels. Take note of any restraints, like water quality, pH, and incompatible mixes.
  2. Always conduct a jar test before adding a new input to your crop input program, especially if there is insufficient information on the agricultural inputs you plan to use.
  3. Run a phytotoxicity trial by spraying a small group of different plant species to determine if the tank mix is safe for application.
  4. Clean your spray rig before use to avoid unforeseen chemical and physical incompatibilities in your tank.
  5. Make sure all components of your spray rig have the correct filters.
  6. Don’t add products when there is an insufficient volume of carrier in the spray tank.
  7. Use the right carrier volumes. Normally, this is 50% full for water, or 75% full for fertilizer.
  8. Know the differences between fertilizer and water carriers.
  9. Decide which inputs you are going to mix in the tank before you tank mix. Don’t make these decisions while loading the sprayer.
  10. Mix products in the correct sequence. If you are unsure, ask your crop adviser or the manufacturer.
  11. Be patient and give each product time to dissolve and disperse. Don’t add products too quickly.
  12. Don’t mix with too much agitation, as this can cause foaming with liquid flowables.
  13. Too little agitation can keep dry formulas from dissolving.
  14. Reagitate, as needed for water dispersible granules (WDG), wettable powders (WP), suspension, concentrates (SC), and emulsifiable concentrates (EC).
  15. Give extra time for dry products to mix into cold carriers.
  16. Don’t mix antimicrobials with biologicals because antimicrobials can kill the microbes in the tank.
  17. Avoid combining solutions that have not been tested.
  18. Check your containers to ensure formulations haven’t separated into layers and are thoroughly mixed before spraying.
  19. Dress for the job. Wearing proper personal protective gear, like goggles or a face shield, long sleeves, gloves, pants, and safety footwear are best practices for spray day!
  20. Contact the manufacturer of the products you’re using, extension educators, and specialists if you have questions.

An Extra Level of Precaution: Conduct a Jar Test

A little extra planning and testing can go a long way. Interested in spraying a new agricultural input in your field? Consider doing a jar test to ensure there are no unforeseen reactions.

A jar test provides the grower with the ability to test the same level of concentration as their tank mix. While jar tests are a great choice to check for physical incompatibilities, they cannot reveal chemical incompatibilities, so conduct a spray test too, if needed.

The things you’ll need for a jar test include:

  • The inputs you’re testing
  • A 500 mL screw top jar
  • Eye droppers for measuring chemicals
  • Water or fertilizer, depending on the desired carrier

Place inputs in the jar in the appropriate ratios and order depending on the desired tank application. Then, cap the jar and shake well. Leave the jar for at least two hours, but preferably overnight.

Signs of physical incompatibilities include flocculation, precipitation, curdling, gelling, or formation of a sludge-like mix. Settling of flowable or powder products is normal.

Note: If it’s hard to resuspend sediments, extra agitation during spraying may be needed to avoid blockage or uneven application. If the mixture appears to be incompatible (see signs above), take steps to improve compatibility by adding a compatibility agent, evaluating the mixing order, or adding additional water.

A jar test can help ensure you don’t clog your sprayer. If there are no formulation or physical incompatibilities once the chemicals are mixed, check for chemical incompatibilities. Then, mix in the tank and spray!

Steps for Tank-Mixing Agricultural Products

First, read the labels and check the quality of your carrier beforehand to establish a baseline for pH, hardness, bicarbonate, salinity, or total dissolved salts.

Once you know the amounts and order of products you’ll be mixing in the tank, fill the tank half full of water or 3⁄4 full of fertilizer, depending on your desired carrier. Never add agricultural products to an empty tank.

Agitate all the product you will be using before adding them into the tank mix. Agitation can help achieve a more even application in your fields.

Then, agitate the carrier in your tank and begin adding the agricultural inputs. Use the acronym W.A.L.E.S when adding products to the tank.

W: Wettable powders or dry formulations (WP/W, WDG, WSP, or DF)

A: Agitate the mix until the powders are fully dissolved

L: Liquid flowables (L, F, SC)

E: Emulsifiable concentrates (EC, then ME)

S: Surfactants and other adjuvants

Allow adequate time for each product to mix. Once all the products are in, finish filling the tank with your carrier. Test the pH to make sure everything is safe for application.

Then, head out into the fields to apply the tank mix to your crops.

Want to Really Optimize Your Yield Potential with Your Tank Mix?

Inside your soil is a microbiome, or community of microorganisms. Unfortunately, 75% of all beneficial microbes in farm soil are either dormant, unhealthy, or starving. When active, native microbes can support your crop throughout the growing season. How?

An active and well-fed microbiome:

PhycoTerra® is a pasteurized, shelf-stable, carbon microbial food source with minimal storage requirements. It can be applied to any type of soil to promote the well-being of any type of crop.

You can mix PhycoTerra® with liquid fertilizers, like nitrogen, phosphate starter or pop-up fertilizers, fertilizer blend partners, and specialty fertilizers. Activated microbes help make the most of your fertilizer application!

Our product can also be mixed with fertilizer blend partners, like enzymes, inoculants, seaweeds, kelps, humic acids, and other living biological products. Stacking carbon products is a smart decision for any field.

Common crop inputs, like herbicides, fungicides, and insecticides are also easily applied and mixed with PhycoTerra®.

This carbon-rich product is a smart way to make the most of any tank mix.

Tank-Mixing Biologicals: Add Live Microbes and Inoculants to Support Soil Health

The hardest part about adding biologicals to your tank mix – they’re alive. They also need to stay alive to support your crops. Follow the best practices to keep microbes and inoculum alive before, during, and after you spray.

Storage, Transportation, and Pre-Field Application

Improper storage, on your farm or in transportation, can kill your microbes or inoculants before they have a chance to enter your spray tank.

Once at your farm, keep-in-mind direct sunlight and heat can kill inoculants or live biological products. Store in a cool place out of the sun. The preferred storage to protect inoculants is in a cool, dry place. Most of these products also require specific storage that doesn’t expose them to freezing temperatures.

Also, always check the expiration date! If you’re not sure if your biologicals are alive or not, have a lab measure the agricultural product for colony-forming unit counts (CFU).

Protect Biologicals in Your Tank Mix

Bactericides, biocides (like copper and manganese), and treated water can kill microbes and inoculants in your tank.

Don’t mix biologicals with competing microbes, which could consume one another. Some competing microbes can be applied in the same tank if they’re sprayed within two to four hours of mixing.

Due to lower concentrations when sprayed, the organisms won’t feed off one another once sprayed.

Neutralize pH When Needed

Some agricultural products will require you to neutralize the pH before tank-mixing with other living biologicals or inoculants. You can determine if neutralization is needed by reading the labels of each product before tank-mixing.

For example, when using PhycoTerra® ST, we suggest growers mix our award-winning seed treatment with potassium hydroxide – 45% (KOH) – if applied with biologicals that are sensitive to low pH levels. Growers should add a 5.65 liquid oz. of KOH with a full jug (2.5 gal) of PhycoTerra® ST. When mixing with KOH, follow all safety precautions on the label.

Mix the two together, either with a stir stick or a power drill with a paint mixer attachment. Then, allow the jug to settle and wait 2 minutes for the stabilizer to neutralize the pH to protect biologicals.

Read the full instructions here.

Spraying Best Practices for Biologicals

If you can, spray your biologicals with nutritional treatment products for your crops. Often, what feeds the plants also feeds the microbes.

If you’re going to mix with fertilizers, avoid synthetics with a high-level electric conductivity (EC).

Once you’re ready to spray, pick a biological safe nozzle spray level. Biologicals can be sprayed safely at a 65 psi nozzle pressure, or lower, to protect microbes.

Ask Yourself the Following Before You Start Tank-Mixing

Accidents happen but running through this list of questions can decrease your chance of accidents and incompatibilities.

  • Have I read the label to ensure incompatibilities are avoided?
  • If there is no label or if there’s a low number of publications, have I sought out advice from an expert?
  • Have I done a jar test to avoid physical incompatibilities?
  • Should I conduct a spray test to avoid chemical incompatibilities?
  • Do I have the right sequence and amount for each ingredient?
  • Am I mixing microbials with antimicrobials?
  • Are there evolving rules or instructions to consider?
  • Am I spraying according to conditions and pressures?
  • Did I double-check my equipment and filters?
  • Do I have enough time to mix each product and spray without leaving the chemicals in the tank overnight?

While there are Mix Tank Apps growers can use to tank mix agricultural inputs, the more you know about the products you’re putting into your sprayer, the better your odds of avoiding a frustrating situation or disaster.

Knowing the answers to the questions above can ensure you’re making the most of your time and money when it’s spray day. Revisit the questions each time you plan to tank mix.

Ready to add a soil microbial food to your tank mix? Reach out to learn how PhycoTerra® can support the health of your soil, ROI, and yield potential.